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Significant differences in genotoxicity induced by retrovirus integration in human T cells and induced pluripotent stem cells
Retrovirus is frequently used in the genetic modification of mammalian cells and the establishment of induced pluripotent stem cells (iPSCs) via cell reprogramming. Vector-induced genotoxicity could induce profound effect on the physiology and function of these stem cells and their differentiated pr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605218/ https://ncbi.nlm.nih.gov/pubmed/23376452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2013.01.009 |
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