Interference with Akt signaling protects against myocardial infarction and death by limiting the consequences of oxidative stress

The intricacy of multiple feedback loops in the pathways downstream of Akt allows Akt to control multiple cellular processes in the cardiovascular system and precludes inferring consequences of its activation in specific pathological conditions. Akt1, the major Akt isoform in heart and vasculature,...

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Detalhes bibliográficos
Main Authors: Kerr, Bethany A., Ma, Lining, West, Xiaoxia Z., Ding, Liang, Malinin, Nikolay L., Weber, Malory E., Tischenko, Mira, Goc, Anna, Somanath, Payaningal R., Penn, Marc S., Podrez, Eugene A., Byzova, Tatiana V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971949/
https://ncbi.nlm.nih.gov/pubmed/23921086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003948
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