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Akt1 Signaling Regulates Integrin Activation, Matrix Recognition, and Fibronectin Assembly

Akt, a serine-threonine kinase, regulates multiple cellular processes in vascular cells. We have previously documented that Akt activates integrins and Akt1 deficiency results in matrix abnormalities in skin and blood vessels in vivo. Based on these observations, we hypothesized that Akt1 is necessa...

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Detalhes bibliográficos
Main Authors: Somanath, Payaningal R., Kandel, Eugene S., Hay, Nissim, Byzova, Tatiana V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731941/
https://ncbi.nlm.nih.gov/pubmed/17562714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700241200
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