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Akt1 Signaling Regulates Integrin Activation, Matrix Recognition, and Fibronectin Assembly

Akt, a serine-threonine kinase, regulates multiple cellular processes in vascular cells. We have previously documented that Akt activates integrins and Akt1 deficiency results in matrix abnormalities in skin and blood vessels in vivo. Based on these observations, we hypothesized that Akt1 is necessa...

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Sonraí Bibleagrafaíochta
Main Authors: Somanath, Payaningal R., Kandel, Eugene S., Hay, Nissim, Byzova, Tatiana V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731941/
https://ncbi.nlm.nih.gov/pubmed/17562714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700241200
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