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Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Akt kinases control essential cellular functions, including proliferation, apoptosis, metabolism and transcription, and have been proposed as promising targets for treatment of angiogenesis-dependent pathologies, such as cancer and ischemic injury. But their precise roles in neovascularization remai...

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Bibliographic Details
Main Authors: Chen, Juhua, Somanath, Payaningal R, Razorenova, Olga, Chen, William S, Hay, Nissim, Bornstein, Paul, Byzova, Tatiana V
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277080/
https://ncbi.nlm.nih.gov/pubmed/16227992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1307
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