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Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Akt kinases control essential cellular functions, including proliferation, apoptosis, metabolism and transcription, and have been proposed as promising targets for treatment of angiogenesis-dependent pathologies, such as cancer and ischemic injury. But their precise roles in neovascularization remai...

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Detalhes bibliográficos
Main Authors: Chen, Juhua, Somanath, Payaningal R, Razorenova, Olga, Chen, William S, Hay, Nissim, Bornstein, Paul, Byzova, Tatiana V
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277080/
https://ncbi.nlm.nih.gov/pubmed/16227992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1307
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