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Differential effects of Akt1 signaling on short-versus long-term consequences of myocardial infarction and reperfusion injury

A specific role for Akt1 in events following myocardial infarction (MI) and ischemia/reperfusion (I/R) injury is not known. We aimed to determine whether Akt1 deletion in in vivo mouse models of MI and after ischemia I/R injury would alter myocyte survival, cardiac function, and fibrosis. Akt1(+/+)...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Ma, Lining, Kerr, Bethany A, Prasad, Sathyamangla V Naga, Byzova, Tatiana V, Somanath, Payaningal R
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447480/
https://ncbi.nlm.nih.gov/pubmed/25046438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2014.95
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