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Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges

Recent results confirm that long-term expression of therapeutic transgenes can be achieved by using a transposon-based system in primary stem cells and in vivo. Transposable elements are natural DNA transfer vehicles that are capable of efficient genomic insertion. The latest generation, Sleeping Be...

詳細記述

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書誌詳細
主要な著者: Izsvák, Zsuzsanna, Hackett, Perry B., Cooper, Laurence J.N., Ivics, Zoltán
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971908/
https://ncbi.nlm.nih.gov/pubmed/20652893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201000027
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