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Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges
Recent results confirm that long-term expression of therapeutic transgenes can be achieved by using a transposon-based system in primary stem cells and in vivo. Transposable elements are natural DNA transfer vehicles that are capable of efficient genomic insertion. The latest generation, Sleeping Be...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971908/ https://ncbi.nlm.nih.gov/pubmed/20652893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201000027 |
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