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The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition

Sleeping Beauty (SB) is the most active Tc1/ mariner-type transposon in vertebrates. SB contains two transposase-binding sites (DRs) at the end of each terminal inverted repeat (IR), a feature termed the IR/DR structure. We investigated the involvement of cellular proteins in the regulation of SB tr...

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Detalhes bibliográficos
Main Authors: Zayed, Hatem, Izsvák, Zsuzsanna, Khare, Dheeraj, Heinemann, Udo, Ivics, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154227/
https://ncbi.nlm.nih.gov/pubmed/12711676
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