Germline BRCA mutation does not prevent response to taxane-based therapy for the treatment of castration-resistant prostate cancer

OBJECTIVE: To investigate the relationship between BRCA mutation status and response to taxane-based chemotherapy, since BRCA mutation carriers with prostate cancer appear to have worse survival than non-carriers and docetaxel improves survival in patients with castration-resistant prostate cancer....

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Autors principals: Gallagher, David J., Cronin, Angel M., Milowsky, Matthew I., Morris, Michael J., Bhatia, Jasmine, Scardino, Peter T., Eastham, James A., Offit, Kenneth, Robson, Mark E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971723/
https://ncbi.nlm.nih.gov/pubmed/21756279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2011.10292.x
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