Germline BRCA mutations denote a clinicopathologic subset of prostate cancer

PURPOSE: Increased prostate cancer risk has been reported for BRCA mutation carriers but BRCA-associated clinicopathologic features have not been clearly defined. EXPERIMENTAL DESIGN: We determined BRCA mutation prevalence in 832 Ashkenazi Jewish (AJ) men diagnosed with localized prostate cancer bet...

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Detalhes bibliográficos
Main Authors: Gallagher, David J., Gaudet, Mia M., Pal, Prodipto, Kirchhoff, Tomas, Balistreri, Lisa, Vora, Kinjal, Bhatia, Jasmine, Stadler, Zsofia, Fine, Samson W., Reuter, Victor, Zelefsky, Michael, Morris, Michael J., Scher, Howard I., Klein, Robert J., Norton, Larry, Eastham, James, Scardino, Peter, Robson, Mark E., Offit, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713614/
https://ncbi.nlm.nih.gov/pubmed/20215531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2871
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