Germline BRCA mutations denote a clinicopathologic subset of prostate cancer

PURPOSE: Increased prostate cancer risk has been reported for BRCA mutation carriers but BRCA-associated clinicopathologic features have not been clearly defined. EXPERIMENTAL DESIGN: We determined BRCA mutation prevalence in 832 Ashkenazi Jewish (AJ) men diagnosed with localized prostate cancer bet...

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Bibliografski detalji
Glavni autori: Gallagher, David J., Gaudet, Mia M., Pal, Prodipto, Kirchhoff, Tomas, Balistreri, Lisa, Vora, Kinjal, Bhatia, Jasmine, Stadler, Zsofia, Fine, Samson W., Reuter, Victor, Zelefsky, Michael, Morris, Michael J., Scher, Howard I., Klein, Robert J., Norton, Larry, Eastham, James, Scardino, Peter, Robson, Mark E., Offit, Kenneth
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713614/
https://ncbi.nlm.nih.gov/pubmed/20215531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2871
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