Germline BRCA mutations denote a clinicopathologic subset of prostate cancer

PURPOSE: Increased prostate cancer risk has been reported for BRCA mutation carriers but BRCA-associated clinicopathologic features have not been clearly defined. EXPERIMENTAL DESIGN: We determined BRCA mutation prevalence in 832 Ashkenazi Jewish (AJ) men diagnosed with localized prostate cancer bet...

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Autori principali: Gallagher, David J., Gaudet, Mia M., Pal, Prodipto, Kirchhoff, Tomas, Balistreri, Lisa, Vora, Kinjal, Bhatia, Jasmine, Stadler, Zsofia, Fine, Samson W., Reuter, Victor, Zelefsky, Michael, Morris, Michael J., Scher, Howard I., Klein, Robert J., Norton, Larry, Eastham, James, Scardino, Peter, Robson, Mark E., Offit, Kenneth
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713614/
https://ncbi.nlm.nih.gov/pubmed/20215531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2871
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