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BRCA Germline Mutations in Jewish Patients With Pancreatic Adenocarcinoma

PURPOSE: The prognostic significance of germline BRCA1 and BRCA2 mutations in Jewish patients with pancreatic adenocarcinoma (PAC) is unknown. Our objective was to define the prevalence of BRCA1 and BRCA2 in an unselected group of Jewish patients and to compare the clinical characteristics and overa...

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Detalhes bibliográficos
Main Authors: Ferrone, Cristina R., Levine, Douglas A., Tang, Laura H., Allen, Peter J., Jarnagin, William, Brennan, Murray F., Offit, Kenneth, Robson, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657622/
https://ncbi.nlm.nih.gov/pubmed/19064968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.18.5546
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