BRCA1/BRCA2 Germline Mutation Carriers and Sporadic Pancreatic Ductal Adenocarcinoma

BACKGROUND: The outcomes of sporadic pancreatic ductal adenocarcinoma (PDAC) patients with germline mutations of BRCA1/BRCA2 remains unclear. The prognostic significance of BRCA1/BRCA2 mutations on survival is not well established. STUDY DESIGN: We performed targeted next-generation sequencing (NGS)...

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Detalhes bibliográficos
Publicado no:J Am Coll Surg
Main Authors: Blair, Alex B, Groot, Vincent P, Gemenetzis, Georgios, Wei, Jishu, Cameron, John L., Weiss, Matthew J., Goggins, Michael, Wolfgang, Christopher L., Yu, Jun, He, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178809/
https://ncbi.nlm.nih.gov/pubmed/29309945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2017.12.021
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