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Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262
In the ER (endoplasmic reticulum) of human cells, disulfide bonds are predominantly generated by the two isoforms of Ero1 (ER oxidoreductin-1): Ero1α and Ero1β. The activity of Ero1α is tightly regulated through the formation of intramolecular disulfide bonds to help ensure balanced ER redox conditi...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971451/ https://ncbi.nlm.nih.gov/pubmed/27919037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130124 |
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