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Disulphide production by Ero1α–PDI relay is rapid and effectively regulated
The molecular networks that control endoplasmic reticulum (ER) redox conditions in mammalian cells are incompletely understood. Here, we show that after reductive challenge the ER steady-state disulphide content is restored on a time scale of seconds. Both the oxidase Ero1α and the oxidoreductase pr...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2957208/ https://ncbi.nlm.nih.gov/pubmed/20802462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.203 |
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