Incremental value of rare genetic variants for the prediction of multifactorial diseases

BACKGROUND: It is often assumed that rare genetic variants will improve available risk prediction scores. We aimed to estimate the added predictive ability of rare variants for risk prediction of common diseases in hypothetical scenarios. METHODS: In simulated data, we constructed risk models with a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mihaescu, Raluca, Pencina, Michael J, Alonso, Alvaro, Lunetta, Kathryn L, Heckbert, Susan R, Benjamin, Emelia J, JW Janssens, A Cecile
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971349/
https://ncbi.nlm.nih.gov/pubmed/23961719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm480
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi