Structural polymorphism in the N-terminal oligomerization domain of NPM1

Nucleophosmin (NPM1) is a multifunctional phospho-protein with critical roles in ribosome biogenesis, tumor suppression, and nucleolar stress response. Here we show that the N-terminal oligomerization domain of NPM1 (Npm-N) exhibits structural polymorphism by populating conformational states ranging...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mitrea, Diana M., Grace, Christy R., Buljan, Marija, Yun, Mi-Kyung, Pytel, Nicholas J., Satumba, John, Nourse, Amanda, Park, Cheon-Gil, Madan Babu, M., White, Stephen W., Kriwacki, Richard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970533/
https://ncbi.nlm.nih.gov/pubmed/24616519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321007111
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi