A carregar...

Intrinsically Unstructured Domains of Arf and Hdm2 Form Bi-molecular Oligomeric Structures In Vitro and In Vivo

Arf, Hdm2 and p53 regulate the tumor suppressor pathway that is most frequently disrupted in human cancer. In the absence of tumorigenic stress, Hdm2 actively attenuates p53-dependent cell cycle arrest and apoptosis by mediating ubiquitination-dependent degradation of p53. Mitogenic stress activates...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sivakolundu, Sivashankar G., Nourse, Amanda, Moshiach, Simon, Bothner, Brian, Ashley, Chimere, Satumba, John, Lahti, Jill, Kriwacki, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612038/
https://ncbi.nlm.nih.gov/pubmed/18809412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.019
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!