Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation

The multifunctional Creb-binding protein (CBP) protein plays a pivotal role in many critical cellular processes. Here we demonstrate that the bromodomain of CBP binds to histone H3 acetylated on lysine 56 (K56Ac) with higher affinity than to its other monoacetylated binding partners. We show that au...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Das, Chandrima, Roy, Siddhartha, Namjoshi, Sarita, Malarkey, Christopher S., Jones, David N. M., Kutateladze, Tatiana G., Churchill, Mair E. A., Tyler, Jessica K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970516/
https://ncbi.nlm.nih.gov/pubmed/24616510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319122111
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares