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Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation
The multifunctional Creb-binding protein (CBP) protein plays a pivotal role in many critical cellular processes. Here we demonstrate that the bromodomain of CBP binds to histone H3 acetylated on lysine 56 (K56Ac) with higher affinity than to its other monoacetylated binding partners. We show that au...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970516/ https://ncbi.nlm.nih.gov/pubmed/24616510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319122111 |
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