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Rh(I)-Catalyzed Decarbonylative Spirocyclization via C–C Cleavage of Benzocyclobutenones: An Efficient Approach to Access Functionalized Spirocycles

We describe a rhodium-catalyzed all-carbon spirocenter formation through a decarbonylative coupling of trisubstituted cyclic olefins and benzocyclobutenones via C–C activation. A [Rh(CO)(2)Cl](2)/P(C(6)F(5))(3) metal-ligand combination was found to catalyze this transformation most efficiently. A ra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Tao, Savage, Nikolas A., Dong, Guangbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970409/
https://ncbi.nlm.nih.gov/pubmed/24446067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310149
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