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A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells
Changes in the levels of specific microRNAs (miRNAs) can reduce glucose-stimulated insulin secretion and increase beta-cell apoptosis, two causes of islet dysfunction and progression to type 2 diabetes. Studies have shown that single nucleotide polymorphisms (SNPs) within miRNA genes can affect thei...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Milan
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969511/ https://ncbi.nlm.nih.gov/pubmed/23828613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00592-013-0499-1 |
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