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Epigenetic modification restores functional PR expression in endometrial cancer cells

Endometrial cancer, the most common gynecologic malignancy, is a hormonally-regulated tumor. Response to progestin-based therapy correlates positively with progesterone receptor (PR) expression. However, many endometrial tumors have low levels or loss of PR, limiting the clinical application of prog...

詳細記述

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書誌詳細
主要な著者: Yang, Shujie, Xiao, Xue, Jia, Yichen, Liu, Xiaoyue, Zhang, Yuping, Devor, Eric J., Meng, Xiangbing, Thiel, Kristina W., Leslie, Kimberly K.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969402/
https://ncbi.nlm.nih.gov/pubmed/23888956
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