Systematic dissection of the mechanisms underlying progesterone receptor downregulation in endometrial cancer

Progesterone, acting through its receptor, PR (progesterone receptor), is the natural inhibitor of uterine endometrial carcinogenesis by inducing differentiation. PR is downregulated in more advanced cases of endometrial cancer, thereby limiting the effectiveness of hormonal therapy. Our objective w...

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Gardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Yang, Shujie, Jia, Yichen, Liu, Xiaoyue, Winters, Christopher, Wang, Xinjun, Zhang, Yuping, Devor, Eric J., Hovey, Adriann M., Reyes, Henry D., Xiao, Xue, Xu, Yang, Dai, Donghai, Meng, Xiangbing, Thiel, Kristina W., Domann, Frederick E., Leslie, Kimberly K.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259437/
https://ncbi.nlm.nih.gov/pubmed/25229191
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