Epigenetic modification restores functional PR expression in endometrial cancer cells

Endometrial cancer, the most common gynecologic malignancy, is a hormonally-regulated tumor. Response to progestin-based therapy correlates positively with progesterone receptor (PR) expression. However, many endometrial tumors have low levels or loss of PR, limiting the clinical application of prog...

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Autors principals: Yang, Shujie, Xiao, Xue, Jia, Yichen, Liu, Xiaoyue, Zhang, Yuping, Devor, Eric J., Meng, Xiangbing, Thiel, Kristina W., Leslie, Kimberly K.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969402/
https://ncbi.nlm.nih.gov/pubmed/23888956
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