Knockdown of MTDH Sensitizes Endometrial Cancer Cells to Cell Death Induction by Death Receptor Ligand TRAIL and HDAC Inhibitor LBH589 Co-Treatment

Understanding the molecular underpinnings of chemoresistance is vital to design therapies to restore chemosensitivity. In particular, metadherin (MTDH) has been demonstrated to have a critical role in chemoresistance. Over-expression of MTDH correlates with poor clinical outcome in breast cancer, ne...

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Bibliographische Detailangaben
Hauptverfasser: Meng, Xiangbing, Brachova, Pavla, Yang, Shujie, Xiong, Zhi, Zhang, Yuping, Thiel, Kristina W., Leslie, Kimberly K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110819/
https://ncbi.nlm.nih.gov/pubmed/21687633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020920
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