Radiosynthesis and Biological Evaluation of N-[(18)F]Labeled Glutamic Acid as a Tumor Metabolic Imaging Tracer

We have previously reported that N-(2-[(18)F]fluoropropionyl)-L-methionine ([(18)F]FPMET) selectively accumulates in tumors. However, due to the poor pharmacokinetics of [(18)F]FPMET in vivo, the potential clinical translation of this observation is hampered. In this study, we rationally designed an...

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Autors principals: Hu, Kongzhen, Du, Kan, Tang, Ganghua, Yao, Shaobo, Wang, Hongliang, Liang, Xiang, Yao, Baoguo, Huang, Tingting, Zang, Linquan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969356/
https://ncbi.nlm.nih.gov/pubmed/24681642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093262
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