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Radiosynthesis and Biological Evaluation of N-[(18)F]Labeled Glutamic Acid as a Tumor Metabolic Imaging Tracer
We have previously reported that N-(2-[(18)F]fluoropropionyl)-L-methionine ([(18)F]FPMET) selectively accumulates in tumors. However, due to the poor pharmacokinetics of [(18)F]FPMET in vivo, the potential clinical translation of this observation is hampered. In this study, we rationally designed an...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969356/ https://ncbi.nlm.nih.gov/pubmed/24681642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093262 |
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