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(18)F-FP-PEG(2)-β-Glu-RGD(2): A Symmetric Integrin α(v)β(3)-Targeting Radiotracer for Tumor PET Imaging

Radiolabeled cyclic arginine-glycine-aspartic (RGD) peptides can be used for noninvasive determination of integrin α(v)β(3) expression in tumors. In this study, we performed radiosynthesis and biological evaluation of a new (18)F-labeled RGD homodimeric peptide with one 8-amino-3,6-dioxaoctanoic aci...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hu, Kongzhen, Tang, Xiaolan, Tang, Ganghua, Yao, Shaobo, Yao, Baoguo, Wang, Hongliang, Nie, Dahong, Liang, Xiang, Tang, Caihua, He, Shanzhen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580323/
https://ncbi.nlm.nih.gov/pubmed/26397833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138675
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