Radiosynthesis and preliminary biological evaluation of N-(2-[(18)F]fluoropropionyl)-L-glutamine as a PET tracer for tumor imaging

In this study, radiosynthesis and biological evaluation of a new [(18)F]labeled glutamine analogue, N-(2-[(18)F]fluoropropionyl)-L-glutamine ([(18)F]FPGLN) for tumor PET imaging are performed. [(18)F]FPGLN was synthesized via a two-step reaction sequence from 4-nitrophenyl-2-[(18)F]fluoropropionate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tang, Caihua, Tang, Ganghua, Gao, Siyuan, Liu, Shaoyu, Wen, Fuhua, Yao, Baoguo, Nie, Dahong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085140/
https://ncbi.nlm.nih.gov/pubmed/27153544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9115
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