Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [(18)F]fluorophenylglutamine and [(18)F]fluorobiphenylglutamine.

INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis. The development of radiolabeled glutamine derivatives could be a useful molecular imaging tool for visualizing these tumors...

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Bibliografiska uppgifter
I publikationen:Nucl Med Biol
Huvudupphovsmän: Baguet, Tristan, Verhoeven, Jeroen, Pauwelyn, Glenn, Hu, Jiyun, Lambe, Patricia, De Lombaerde, Stef, Piron, Sarah, Donche, Sam, Descamps, Benedicte, Goethals, Ingeborg, Vanhove, Christian, De Vos, Filip, Beyzavi, M. Hassan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814958/
https://ncbi.nlm.nih.gov/pubmed/32447069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2020.03.006
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