Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [(18)F]fluorophenylglutamine and [(18)F]fluorobiphenylglutamine.

INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis. The development of radiolabeled glutamine derivatives could be a useful molecular imaging tool for visualizing these tumors...

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Publicat a:Nucl Med Biol
Autors principals: Baguet, Tristan, Verhoeven, Jeroen, Pauwelyn, Glenn, Hu, Jiyun, Lambe, Patricia, De Lombaerde, Stef, Piron, Sarah, Donche, Sam, Descamps, Benedicte, Goethals, Ingeborg, Vanhove, Christian, De Vos, Filip, Beyzavi, M. Hassan
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814958/
https://ncbi.nlm.nih.gov/pubmed/32447069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2020.03.006
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