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Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [(18)F]fluorophenylglutamine and [(18)F]fluorobiphenylglutamine.

INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis. The development of radiolabeled glutamine derivatives could be a useful molecular imaging tool for visualizing these tumors...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nucl Med Biol
Κύριοι συγγραφείς: Baguet, Tristan, Verhoeven, Jeroen, Pauwelyn, Glenn, Hu, Jiyun, Lambe, Patricia, De Lombaerde, Stef, Piron, Sarah, Donche, Sam, Descamps, Benedicte, Goethals, Ingeborg, Vanhove, Christian, De Vos, Filip, Beyzavi, M. Hassan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814958/
https://ncbi.nlm.nih.gov/pubmed/32447069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2020.03.006
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