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Tumor-Associated Mutant p53 Drives the Warburg Effect
Tumor cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect. Its mechanism is not well-understood. The tumor suppressor gene p53 is frequently mutated in tumors. Many tumor-associated mutant p53 (mutp53) proteins not only lose tumor suppressive fu...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969270/ https://ncbi.nlm.nih.gov/pubmed/24343302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3935 |
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