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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
Regulation of energy metabolism is a novel function of p53 in tumor suppression. Parkin (PARK2), a Parkinson disease-associated gene, is a potential tumor suppressor whose expression is frequently diminished in tumors. Here Parkin was identified as a p53 target gene that is an important mediator of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182683/ https://ncbi.nlm.nih.gov/pubmed/21930938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113884108 |
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