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Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

Regulation of energy metabolism is a novel function of p53 in tumor suppression. Parkin (PARK2), a Parkinson disease-associated gene, is a potential tumor suppressor whose expression is frequently diminished in tumors. Here Parkin was identified as a p53 target gene that is an important mediator of...

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מידע ביבליוגרפי
Main Authors: Zhang, Cen, Lin, Meihua, Wu, Rui, Wang, Xiaowen, Yang, Bo, Levine, Arnold J., Hu, Wenwei, Feng, Zhaohui
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182683/
https://ncbi.nlm.nih.gov/pubmed/21930938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113884108
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