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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

Whereas cell cycle arrest, apoptosis, and senescence are traditionally thought of as the major functions of the tumor suppressor p53, recent studies revealed two unique functions for this protein: p53 regulates cellular energy metabolism and antioxidant defense mechanisms. Here, we identify glutamin...

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Detalhes bibliográficos
Main Authors: Hu, Wenwei, Zhang, Cen, Wu, Rui, Sun, Yvonne, Levine, Arnold, Feng, Zhaohui
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867677/
https://ncbi.nlm.nih.gov/pubmed/20378837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001006107
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