Tumor-Associated Mutant p53 Drives the Warburg Effect

Tumor cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect. Its mechanism is not well-understood. The tumor suppressor gene p53 is frequently mutated in tumors. Many tumor-associated mutant p53 (mutp53) proteins not only lose tumor suppressive fu...

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Autori principali: Zhang, Cen, Liu, Juan, Liang, Yingjian, Wu, Rui, Zhao, Yuhan, Hong, Xuehui, Lin, Meihua, Yu, Haiyang, Liu, Lianxin, Levine, Arnold J., Hu, Wenwei, Feng, Zhaohui
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969270/
https://ncbi.nlm.nih.gov/pubmed/24343302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3935
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