A Conserved Mechanism for Binding of p53 DNA-Binding Domain and Anti-Apoptotic Bcl-2 Family Proteins

The molecular interaction between tumor suppressor p53 and the anti-apoptotic Bcl-2 family proteins plays an essential role in the transcription-independent apoptotic pathway of p53. In this study, we investigated the binding of p53 DNA-binding domain (p53DBD) with the anti-apoptotic Bcl-2 family pr...

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Main Authors: Lee, Dong-Hwa, Ha, Ji-Hyang, Kim, Yul, Jang, Mi, Park, Sung Jean, Yoon, Ho Sup, Kim, Eun-Hee, Bae, Kwang-Hee, Park, Byoung Chul, Park, Sung Goo, Yi, Gwan-Su, Chi, Seung-Wook
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Molecular and Cellular Biology 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969048/
https://ncbi.nlm.nih.gov/pubmed/24646834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.0001
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