Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition

The p53, p63, and p73 proteins belong to the p53 family of transcription factors, which play key roles in tumor suppression. Although the transactivation domains (TADs) of the p53 family are intrinsically disordered, these domains are commonly involved in the regulatory interactions with mouse doubl...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Shin, Jae-Sun, Ha, Ji-Hyang, Lee, Dong-Hwa, Ryu, Kyoung-Seok, Bae, Kwang-Hee, Park, Byoung Chul, Park, Sung Goo, Yi, Gwan-Su, Chi, Seung-Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614862/
https://ncbi.nlm.nih.gov/pubmed/25591003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2014.998056
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