Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cells

Granzyme A (GzmA) was first identified as a cytotoxic T lymphocyte protease protein with limited tissue expression. A number of cellular proteins are known to be cleaved by GzmA, and its function is to induce apoptosis. Histones H1, H2B, and H3 were identified as GzmA substrates during apoptotic cel...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Lee, Phil Young, Park, Byoung Chul, Chi, Seung Wook, Bae, Kwang-Hee, Kim, Sunhong, Cho, Sayeon, Kang, Seongman, Kim, Jeong-Hoon, Park, Sung Goo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227298/
https://ncbi.nlm.nih.gov/pubmed/27439606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.10.105
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