Hydrogen Sulfide Attenuates sFlt1-Induced Hypertension and Renal Damage by Upregulating Vascular Endothelial Growth Factor

Soluble fms-like tyrosine kinase 1 (sFlt1), a circulating antiangiogenic protein, is elevated in kidney diseases and contributes to the development of preeclampsia. Hydrogen sulfide is a vasorelaxant and proangiogenic gas with therapeutic potential in several diseases. Therefore, we evaluated the po...

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Bibliografische gegevens
Hoofdauteurs: Holwerda, Kim M., Burke, Suzanne D., Faas, Marijke M., Zsengeller, Zsuzsanna, Stillman, Isaac E., Kang, Peter M., van Goor, Harry, McCurley, Amy, Jaffe, Iris Z., Karumanchi, S. Ananth, Lely, A. Titia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2014
Onderwerpen:
Basic Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968492/
https://ncbi.nlm.nih.gov/pubmed/24335973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013030291
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