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Hydrogen Sulfide Attenuates sFlt1-Induced Hypertension and Renal Damage by Upregulating Vascular Endothelial Growth Factor

Soluble fms-like tyrosine kinase 1 (sFlt1), a circulating antiangiogenic protein, is elevated in kidney diseases and contributes to the development of preeclampsia. Hydrogen sulfide is a vasorelaxant and proangiogenic gas with therapeutic potential in several diseases. Therefore, we evaluated the po...

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Detalhes bibliográficos
Main Authors: Holwerda, Kim M., Burke, Suzanne D., Faas, Marijke M., Zsengeller, Zsuzsanna, Stillman, Isaac E., Kang, Peter M., van Goor, Harry, McCurley, Amy, Jaffe, Iris Z., Karumanchi, S. Ananth, Lely, A. Titia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968492/
https://ncbi.nlm.nih.gov/pubmed/24335973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013030291
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