The Mammalian INDY Homolog Is Induced by CREB in a Rat Model of Type 2 Diabetes

Reduced expression of the INDY (I'm not dead yet) tricarboxylate carrier increased the life span in different species by mechanisms akin to caloric restriction. Mammalian INDY homolog (mIndy, SLC13A5) gene expression seems to be regulated by hormonal and/or nutritional factors. The underlying m...

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Main Authors: Neuschäfer-Rube, Frank, Lieske, Stefanie, Kuna, Manuela, Henkel, Janin, Perry, Rachel J., Erion, Derek M., Pesta, Dominik, Willmes, Diana M., Brachs, Sebastian, von Loeffelholz, Christian, Tolkachov, Alexander, Schupp, Michael, Pathe-Neuschäfer-Rube, Andrea, Pfeiffer, Andreas F.H., Shulman, Gerald I., Püschel, Gerhard P., Birkenfeld, Andreas L.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2014
Teme:
Pathophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968437/
https://ncbi.nlm.nih.gov/pubmed/24222346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0749
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