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The Role of INDY in Metabolic Regulation

Reduced expression of the Indy (I'm Not Dead Yet) gene in D. melanogaster and C. elegans extends longevity. Indy and its mammalian homolog mINDY (Slc13a5, NaCT) are transporters of TCA cycle intermediates, mainly handling the uptake of citrate via the plasma membrane into the cytosol. Deletion...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Willmes, Diana M, Birkenfeld, Andreas L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962103/
https://ncbi.nlm.nih.gov/pubmed/24688728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5936/csbj.201303020
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