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The role of INDY in metabolism, health and longevity
Indy (I’m Not Dead Yet) encodes the fly homolog of a mammalian SLC13A5 plasma membrane transporter. INDY is expressed in metabolically active tissues functioning as a transporter of Krebs cycle intermediates with the highest affinity for citrate. Decreased expression of the Indy gene extends longevi...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460575/ https://ncbi.nlm.nih.gov/pubmed/26106407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00204 |
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