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Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture

Insulin-producing cells (IPCs) derived from human pluripotent stem cells (hPSCs) may be useful in cell therapy and drug discovery for diabetes. Here, we examined various growth factors and small molecules including those previously reported to develop a robust differentiation method for induction of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takeuchi, Hiroki, Nakatsuji, Norio, Suemori, Hirofumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967149/
https://ncbi.nlm.nih.gov/pubmed/24671046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04488
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