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Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture

Insulin-producing cells (IPCs) derived from human pluripotent stem cells (hPSCs) may be useful in cell therapy and drug discovery for diabetes. Here, we examined various growth factors and small molecules including those previously reported to develop a robust differentiation method for induction of...

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Bibliografiske detaljer
Main Authors: Takeuchi, Hiroki, Nakatsuji, Norio, Suemori, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967149/
https://ncbi.nlm.nih.gov/pubmed/24671046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04488
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