Effects of native and myeloperoxidase-modified apolipoprotein A-I on reverse cholesterol transport and atherosclerosis in mice

OBJECTIVE: Preclinical and clinical studies have shown beneficial effects of infusions of apolipoprotein A-I (ApoA-I) on atherosclerosis. ApoA-I is also a target for myeloperoxidase (MPO)-mediated oxidation, leading in vitro to a loss of its ability to promote ABCA1-dependent macrophage cholesterol...

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Detalhes bibliográficos
Main Authors: Hewing, Bernd, Parathath, Saj, Barrett, Tessa, Chung, Wing Ki Kellie, Astudillo, Yaritzy M., Hamada, Tadateru, Ramkhelawon, Bhama, Tallant, Thomas C., Yusufishaq, Mohamed Shaif S., DiDonato, Joseph A., Huang, Ying, Buffa, Jennifer, Berisha, Stela Z., Smith, Jonathan D., Hazen, Stanley L., Fisher, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966977/
https://ncbi.nlm.nih.gov/pubmed/24407029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.303044
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