Modification of High Density Lipoprotein by Myeloperoxidase Generates a Pro-inflammatory Particle

High density lipoprotein (HDL) is the major atheroprotective particle in plasma. Recent studies demonstrate that myeloperoxidase (MPO) binds to HDL in vivo, selectively targeting apolipoprotein A1 (apoA1) of HDL for oxidative modification and concurrent loss in cholesterol efflux and lecithin choles...

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Библиографические подробности
Главные авторы: Undurti, Arundhati, Huang, Ying, Lupica, Joseph A., Smith, Jonathan D., DiDonato, Joseph A., Hazen, Stanley L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781481/
https://ncbi.nlm.nih.gov/pubmed/19726691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047605
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