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Myeloperoxidase, modified lipoproteins, and atherogenesis

Numerous lines of evidence implicate a role for myeloperoxidase (MPO) in the pathogenesis of atherosclerosis. Enriched within vulnerable plaque, MPO serves as an enzymatic source of eicosanoids and bioactive lipids and generates atherogenic forms of both low- and high-density lipoproteins. These fac...

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Detalhes bibliográficos
Main Authors: Nicholls, Stephen J., Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674690/
https://ncbi.nlm.nih.gov/pubmed/19091698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800086-JLR200
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