OSTEOPONTIN BINDING TO LIPOPOLYSACCHARIDE LOWERS TUMOR NECROSIS FACTOR-α AND PREVENTS EARLY ALCOHOL-INDUCED LIVER INJURY IN MICE

RATIONALE: Although osteopontin (OPN) is induced in alcoholic patients, its role in the pathophysiology of alcoholic liver disease (ALD) remains unclear. Increased translocation of lipopolysaccharide (LPS) from the gut is key for the onset of ALD since it promotes macrophage infiltration and activat...

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Detaylı Bibliyografya
Asıl Yazarlar: Ge, Xiaodong, Leung, Tung-Ming, Arriazu, Elena, Lu, Yongke, Urtasun, Raquel, Christensen, Brian, Fiel, Maria Isabel, Mochida, Satoshi, Sørensen, Esben S., Nieto, Natalia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966944/
https://ncbi.nlm.nih.gov/pubmed/24214181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26931
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